12.5 Physiology of the Digestive System

Functions of the Digestive System

The main functions of the digestive system are ingesting food, digesting food, absorbing nutrients, and eliminating waste products. See Table 12.5 for an overview of the functions of the organs of the digestive tract.

Table 12.5. Functions of the Digestive Organs[1]

Organ Major Functions Other Functions
Mouth
  • Ingests food
  • Chews and mixes food
  • Begins chemical breakdown of carbohydrates
  • Moves food into the pharynx
  • Begins breakdown of lipids via lingual lipase
  • Moistens and dissolves food, allowing for taste
  • Cleans and lubricates the teeth and oral cavity
  • Promotes some antimicrobial activity
Pharynx
  • Propels food from the oral cavity to the esophagus
  • Lubricates food and passageways
Esophagus
  • Propels food to the stomach
  • Lubricates food and passageways
Stomach
  • Mixes and churns food with gastric juices to form chyme
  • Begins chemical breakdown of proteins
  • Releases food into the duodenum as chyme
  • Absorbs some fat-soluble substances
  • Possesses antimicrobial functions
  • Stimulates protein-digesting enzymes
  • Secretes intrinsic factor required for vitamin B12 absorption in small intestine
Small Intestine
  • Mixes chyme with digestive juices
  • Propels food at a rate slow enough for digestion and absorption
  • Absorbs breakdown products of carbohydrates, proteins, lipids, and nucleic acids, along with vitamins, minerals, and water
  • Performs physical digestion via segmentation
  • Provides optimal medium for enzymatic activity
Large Intestine
  • Further breaks down food residues
  • Absorbs most residual water, electrolytes, and vitamins produced by enteric bacteria
  • Propels feces toward rectum
  • Eliminates feces
  • Temporarily stores concentrated food residue prior to defecation
  • Eases passage of feces through colon from mucus
Accessory Organs
  • Liver: produces bile salts, which emulsify lipids, aiding their digestion and absorption
  • Gallbladder: stores, concentrates, and releases bile
  • Pancreas: produces digestive enzymes and bicarbonate
  • Help neutralize acidic chyme and provide optimal environment for enzymatic activity

 

Digestive Processes

Digestive processes involve the interaction of several organs and occur gradually as food moves through the gastrointestinal tract. The processes of digestion include six activities: ingestion, propulsion, mechanical digestion, chemical digestion, absorption, and defecation.[2] See Figure 12.13[3] for an illustration of digestive processes.

 

Illustration of digestive processes in human form, with labels for major parts and processes
Figure 12.13 Digestive Processes

Ingestion

Ingestion refers to the intake of food through the mouth where it is chewed and mixed with saliva. Saliva contains enzymes that begin breaking down the carbohydrates and fats in the food. Chewing produces a soft mass of food called a bolus (BŌL-ŭs) that is an appropriate size for swallowing.[4]

Propulsion

Food leaves the mouth when the tongue and pharyngeal muscles propel it into the esophagus. This act of swallowing is an example of propulsion, which refers to the movement of food through the digestive tract. It includes both the voluntary process of swallowing and the involuntary process of peristalsis (per-ĭ-STAL-sĭs). Peristalsis consists of sequential, alternating waves of contraction and relaxation of smooth muscles, which act to propel food through the digestive tract. See Figure 12.14[5] for an illustration of peristalsis. Peristaltic waves also play a role in mixing food with digestive juices. Peristalsis is so powerful that swallowed foods and liquids enter the stomach even if you are standing on your head.[6]

 

Illustration showing peristalsis
Figure 12.14 Peristalsis

Mechanical Digestion

Mechanical digestion is a physical process that does not change the chemical nature of the food but makes it smaller to increase its surface area and mobility. Mechanical digestion starts with chewing and then progresses to mechanical churning of food in the stomach. In the stomach, the bolus of food further breaks apart with more surface area that is exposed to digestive juices of chemical digestion.[7]

Chemical Digestion

Chemical digestion begins in the mouth and is completed in the small intestine. Digestive secretions contain water, enzymes (EN-zīmz), acids, and salts that create an acidic “soup” that breaks down food molecules into their chemical building blocks. For example, proteins are broken down into amino acids (Ā-mē-nō AS-idz).[8]

Absorption

Nutrients (NŪ-trē-ĕntz) are substances that provide nourishment to cells. After food molecules have been broken down during chemical digestion, nutrients enter the bloodstream through the process of absorption (ab-SORP-shŏn). Absorption takes place primarily in the small intestine.

Defecation

During defecation (dĕf-ĕ-KĀ-shŏn), the final step in digestion, undigested materials are expelled from the body as feces.[9]

Additional Terms Related to the Digestive System

Additional common medical terms related to the digestive system include the following:

  • Adhesion (ad-HĒ-zhŏn): Scar tissue from disease or previous surgery that binds anatomic surfaces to each other.
  • Ascites (ă-SĪ-tēz): Abnormal fluid buildup in the abdominal cavity.
  • Dysentery (DIS-ĕn-ter-ē): Inflammation of the intestine presenting with abdominal pain and bloody diarrhea.
  • Dyspepsia (dĭs-PEP-sē-ă): Indigestion.
  • Emesis (ĔM-ĕ-sĭs): Vomiting
  • Flatus (FLĀ-tŭs): Gas in the GI tract.
  • Gastroenteritis (GAS-trō-ĕn-tĕr-Ī-tĭs): Inflammation of the stomach and intestines.
  • Hernia (HUR-nē-ă): Protrusion of an organ through a muscular wall.
  • Melena (mĕ-LĒ-nă): Black, tarry feces that contains blood from the digestive tract.
  • Nausea (NAW-zē-ă): The feeling of an urge to vomit.
  • NPO (en-pee-ō): A commonly used medical abbreviation standing for “nothing by mouth,” meaning not to ingest food, fluids, or medications orally.
  • Obesity (ō-BĒ-sĭ-tē): Increased proportion of fat cells, resulting in excessive body weight in proportion to height.
  • Palpate (PAL-pāt): A physical examination technique where the examiner feels for texture, size, consistency, and location of organs with their hands.
  • Percutaneous endoscopic gastrostomy (pûr-kū-TĀ-nē-ŭs ĕn-DŎS-kŏ-pĭk găs-TRŎS-tŏ-mē) (PEG): A surgical procedure that places a feeding tube into the stomach through the abdominal wall to administer nutrition when swallowing is impaired.
  • Probiotics (prō-bī-OT-ĭks): Normally occurring bacteria that are beneficial for digestion.
  • Reflux (RĒ-flŭks): Abnormal backward flow.
  • Visceral (VĬS-ĕr-ăl): Relating to the organs.
  • Vomiting (VOM-ĭ-ting): Forceful ejection of stomach contents.

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