Reconstitution Practice
Steps to Reconstitution
Reconstitution Knowledge Check
Reconstitution Extended Practice 1
1. Order: 300 mg IM of a drug.
Available: 1000 mg vial with directions to add 4.6 mL SW for injection for a final concentration of 200 mg/mL.
How many mL should be administered (Round to the nearest tenth)?
2. Order: 200,000 units IM of a drug.
Available: 1,000,000 unit vial of a drug has instructions to reconstitute to a concentration of 100,000 units per mL, add 10 mL SW for injection.
How many mL should be administered?
3. Order: 400 mg IM of a drug.
Available: 1 g vials with directions to reconstitute with 8.5 mL of SW for injection for a final concentration of 100 mg/mL.
How many mL should be administered?
4. Order: 500 mg IM.
Available: 1 g vials with instructions to add 3.2 mL of water for injection USP for a final concentration of 250 mg/mL.
How many mL should be administered?
5. Order: 300 mg IM q6h. Label states: This vial contains Oxacillin sodium monohydrate equivalent to 2 grams Oxacillin and 40 mg Dibasic sodium phosphate.
For IM use, add 11.5 mL sterile water for injection, USP. Each 1.5 mL of solution contains 250 mg oxacillin.
How many mL should be administered (Round to the nearest hundredth)?
6. Order: Bicillin C-R (900/300) 1,200,000 units IM stat.
Label states: 900,000 units of Penicillin G benzathine and 300,000 units Penicillin G procaine injectable suspension to yield 1,200,000 units per 2 mL.
How many mL should be administered (Round to the nearest hundredth)?
7. Order: Biaxin 15 mg/kg for a child who weighs 45 lb.
Label states: Measure 55 mL of water using a graduated cylinder. Add half the volume of water to the bottle and shake vigorously. Add the remainder of water to the bottle; shake to yield 125 mg per 5 mL.
How many mL should be administered (Round to the nearest hundredth)?
8. Order: 250 mg IM of a drug.
Available: 500 mg vial with instructions to add 4.3 mL of SW for injection for a final concentration of 100 mg/mL.
How many mL should be administered?
9. Order: 200 mg IM of a drug.
Available: 1 g vials with instructions to add 3.5 mL SW for injection for a final concentration of 250 mg/mL.
How many mL should be administered?
10. Order: Mezlocillin 1500 mg IV q6h.
Label states: For IV use, reconstitute with 30 mL sterile water for injection. Each 30 mL of reconstituted solution will contain 3 g Mezlocillin.
How many mL should be administered?
Answer key is located in the Appendix
Reconstitution Extended Practice 2
1. Order: Fortaz 250 mg IM.
The vial contains 500 mg powder with directions to add 1.5 mL of sterile water for a total volume of 1.8 mL.
How many mL should be administered?
2. Order: Kefzol 0.5 g IM q6h.
Kefzol after reconstitution labeled 225 mg per mL.
How many mL should be administered (Round to the nearest tenth)?
3. Order: Bicillin C-R (900/300) 1,200,000 units IM stat.
Label states: 900,000 units of penicillin G benzathine and 300,000 units penicillin G procaine injectable suspension to yield 1,200,000 units per 2 mL.
How many mL should be administered (Round to the nearest tenth)?
4. Order: Ticarcillin disodium 2 g IM q6h.
The package insert states to reconstitute each 2 g vial with 4 mL of sterile water for injection. Each 5 mL = 1 g.
How many mL will the nurse administer?
5. Order: Ceftriaxone 300 mg IM stat.
Label states: Reconstitute the 750 mg vial with 1.8 mL of sterile water for injection, which results in a total volume of 3.1 mL.
How many mL should be administered (Round to the nearest tenth)?
6. Order: Protamine sulfate 22 mg IVP over ten minutes.
Label states: Reconstitute with 20 mL of sterile water or saline which results in 50 mg/5 mL.
How many mL should be administered (Round to the nearest tenth)?
7. Order: 25 mg of Gentamicin IM.
Label states: Add 1.3 mL sterile diluent to yield 50 mg/1.5 mL.
How many mL of reconstituted solution should be given to the patient?
Answer key is located in the Appendix