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18.15 Ovarian Cysts

An ovarian cyst is a blood- or fluid-filled sac found on or near the ovary. See Figure 18.13[1] for an illustration comparing a normal ovary and an ovary with an ovarian cyst. The most common types of ovarian cysts are functional cysts that form during the menstrual cycle and are usually benign. Functional cysts may be follicle cysts or corpus luteum cysts. When an ovum matures every month, the follicle breaks open to release the ovum. Follicle cysts form when the follicle doesn’t break open to release the ovum and continues to grow into a cyst. Follicle cysts are often asymptomatic and spontaneously resolve in one to three months. Corpus luteum cysts form after the follicle breaks open and releases the ovum, but the empty follicle sac doesn’t shrink. Instead, the sac reseals itself after the egg is released, and fluid builds up inside the sac. Most corpus luteum cysts resolve after a few weeks, but some can grow to almost four inches in diameter. While most small ovarian cysts are asymptomatic, large cysts can bleed, rupture, or twist the ovary and cause severe pain.[2]

Illustration showing locations and appearance of an ovarian cyst
Figure 18.13 Ovarian Cyst

Nonfunctional ovarian cysts may be caused by pelvic infections, endometriosis, polycystic ovary syndrome, or cancer. Women with endometriosis can develop an endometrioma when the endometriosis tissue attaches to the ovary and forms a growth. These cysts can be painful during sex and during the menstrual period. Polycystic ovary syndrome (PCOS) causes ovaries to make many small cysts that can result in infertility. Malignant ovarian cysts that cause ovarian cancer are rare and more common in older women.[3]

Read more about PCOS in the “Polycystic Ovary Syndrome” section.

Ovarian cysts are diagnosed by ultrasound. Symptomatic or large (>10 cm) cysts are removed by laparoscopic ovarian cystectomy, with the goal of preserving normal ovarian tissue and fertility.[4]

If a large ovarian cyst ruptures, it can cause acute, unilateral, lower abdominal pain, classically in the midmenstrual cycle. Rupture may be accompanied by intraperitoneal hemorrhage that may be self-limited or can lead to hemodynamic instability. Women with known ovarian cysts who suddenly develop severe abdominal pain should be evaluated urgently for possible ovarian or tubal torsion. Ovarian and/or tubal torsion requires emergency surgery.[5]


  1. “0e4c3e1ee4d8bc063219ba1ff4b58b46de323ca8” by Rice University/Open Stax is licensed under CC BY 4.0. Access for free at https://openstax.org/books/maternal-newborn-nursing/pages/6-3-benign-growths
  2. Office on Women’s Health. (n.d.). Ovarian cysts. womensthealth.gov. https://womenshealth.gov/a-z-topics/ovarian-cysts
  3. Office on Women’s Health. (n.d.). Ovarian cysts. womensthealth.gov. https://womenshealth.gov/a-z-topics/ovarian-cysts
  4. Laufer, M. R. (2024). Ovarian cysts in infants, children, and adolescents. UpToDate. https://www.uptodate.com/contents/ovarian-cysts-in-infants-children-and-adolescents
  5. Laufer, M. R. (2024). Ovarian cysts in infants, children, and adolescents. UpToDate. https://www.uptodate.com/contents/ovarian-cysts-in-infants-children-and-adolescents
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