Appendix A – Normal Reference Ranges

The following normal reference ranges are used for laboratory tests discussed throughout the book.[1]

Acid Base

Acid Base Normal Reference Ranges
Laboratory Test Normal Reference Range
pH 7.35 – 7.45
PaCO2 35 – 45 mmHg
HCO3 18 – 22 mmol/L
PaO2 80 – 100 mmHg

Cardiac

Cardiac Normal Reference Ranges
Laboratory Test Normal Reference Range
CK 25 – 200 U/L
CKMB 0 – 4 ng/mL
Troponin 0 – 0.4 ng/mL

Cholesterol Panel

Cholesterol Panel Normal Reference Ranges
Laboratory Test Normal Reference Range
Total Cholesterol 3 – 5.5 mmol/L or < 200 mg/dL
HDL 40 – 80 mg/dL
LDL 85 – 125 mg/dL
Triglycerides 50 – 150 mg/dL

Coagulation Profile

Coagulation Profile Normal Reference Ranges
Laboratory Test Normal Reference Range
Prothrombin Time 11 – 14 sec
International Normalized Ratio (INR) 0.9 – 1.2
aPTT (Activated Partial Thromboplastin Time) 20 – 40 sec

Complete Blood Count and Differential

Complete Blood Count and Differential Normal Reference Ranges
Laboratory Test Normal Reference Range
RBC (Red Blood Cell Count) Male: 4.50 – 5.90 million/mm3
Female: 4.00 – 5.20 million/mm3
RDW (Red Blood Cell Distribution Width) 11.5% – 14.5%
Mean Corpuscular Volume (MCV) 80 – 100 fL
Mean Corpuscular Hemoglobin (MCH) 0.4 – 0.5 fmol/cell
Mean Corpuscular Hemoglobin Concentration (MCHC) 30 – 35 g/dL
Hemoglobin Male: 13 – 17 g/dL
Female: 12 – 15 g/dL
Hematocrit Male: 40% – 52%
Female: 36% – 47%
White Blood Cells (WBC) 4000 – 10,000 mm3
Neutrophils 46 – 78%
Lymphocytes 18 – 52%
Monocytes 3 – 10%
Eosinophils 0 – 6%
Basophils 0 – 3%
Platelet Count 150,000 – 400,000 mm3

HbA1C (Hemoglobin A1C)

Hemoglobin A1C Normal Reference Range
Laboratory Test Normal Reference Range
A1C 3.9 – 6.2%

Iron

Iron Studies Normal Reference Ranges
Laboratory Test Normal Reference Range
Total Serum Iron Male: 65 – 180 µg/dL
Female: 30 – 170 µg/dL
Ferritin Male: 12 – 300 ng/mL
Female: 12 – 150 ng/mL
Transferrin 200 – 350 mg/dL
Total Iron-Binding Capacity 45 – 85 µmol/L

Metabolic Panel

Metabolic Panel Normal Reference Ranges
Laboratory Test Normal Reference Range
Sodium 135 – 145 mmol/L
Potassium 3.5 – 5 mmol/L
Chloride 95 – 105 mmol/L
Calcium 8.5 – 10.2 mg/dL
Magnesium 1.5 – 2 mEq/L
Phosphate 0.8 – 1.5 mmol/L
Glucose 65 – 110 mg/dL
Blood Urea Nitrogen (BUN) 8 – 21 mg/dL
Creatinine 0.8 – 1.3 mg/dL

Liver Function Tests

Liver Function Test Normal Reference Ranges
Laboratory Test Normal Reference Range
Alkaline Phosphatase (ALP) 50 – 100 U/L
Alanine Aminotransferase (ALT) 5 – 30 U/L
Aspartate Aminotransferase (AST) 5 – 30 U/L
Albumin 35 – 50 g/L
Total Protein 60 – 80 g/L
Total Bilirubin 2 – 20 µmol/L
Amylase 30 – 125 U/L

Thyroid Hormones

Thyroid Hormone Normal Reference Ranges
Laboratory Test Normal Reference Range
Thyroid Stimulating Hormone (TSH) 0.5 – 5 mIU/L
Total Thyroxine (T4) 4.9 – 11.7 mg/dL
Total Triiodothyronine (T3) 0.7 – 1.5 ng/dL

Urinalysis

Urinalysis Normal Reference Findings
Test or Characteristic Normal Reference Finding
Appearance Clear
Color Amber Yellow
Odor Aromatic
pH 5-8
Protein Negative
Specific Gravity 1.002 – 1.030
Leukocyte Esterase Negative
Nitrites Negative
Ketones Negative
Bilirubin Negative
Crystals Negative
Casts 0 – 4 hyaline casts/lpf
Glucose Negative
WBCs 0 – 5/hpf
RBCs 0 – 5/hpf

Miscellaneous

Miscellaneous Laboratory Test Normal Reference Ranges
Laboratory Test Normal Reference Range
Brain Natriuretic Peptide (BNP) < 100 pg/mL
C-Reactive Protein (CRP) < 5 mg/L
d-Dimer < 500 ng/mL
Lactate Dehydrogenase (LDH) 50-150 U/L

  1. Medscape. (2024). Lab values, normal adult. https://emedicine.medscape.com/article/2172316-overview?

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